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Merck

AR

androgen receptor

동의어:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
종:
UniProtKB ID:
Clone ID:
  • Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(11835) androgen receptor
  • Rat(24208) androgen receptor
  • Zebrafish(100005148) androgen receptor
  • chicken(422165) androgen receptor
  • fruit fly(44503) abdomen rotatum
  • domestic cat(101081787) androgen receptor
  • cow(280675) androgen receptor
  • Horse(100033980) androgen receptor
  • domestic cat(751827) androgen receptor
  • dog(403588) androgen receptor
  • Goat(100860827) androgen receptor
  • Domestic Rabbit(100009193) androgen receptor
  • sheep(443042) androgen receptor
  • domestic guinea pig(100726891) androgen receptor

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Small Molecule - Activator

Product Number
설명
19-Norethindrone, ≥98%, powder,
human, rat
α-Estradiol, powder, ≥98% (TLC),
human, rat
Propylene glycol monomethyl ether acetate, ReagentPlus®, ≥99.5%,
human
Diethylstilbestrol, ≥99% (HPLC),
human, mouse, rat
Resveratrol, ≥99% (HPLC),
human, rat, mouse

Small Molecule - Agonist

Product Number
설명
Testosterone, European Pharmacopoeia (EP) Reference Standard,
human
Stanozolol, European Pharmacopoeia (EP) Reference Standard,
human
Nandrolone decanoate for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Nandrolone decanoate, European Pharmacopoeia (EP) Reference Standard,
human
Testosterone enantate for peak identification, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Antagonist

Product Number
설명
Flutamide for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Bicalutamide, European Pharmacopoeia (EP) Reference Standard,
human
Flutamide, European Pharmacopoeia (EP) Reference Standard,
human
Medroxyprogesterone, ,
rat
β-Zearalenol, ≥98%,
rat

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-phospho-Androgen Receptor (pTyr363) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
western blot
Anti-Androgen Receptor antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunohistochemistry

western blot
Anti-AR antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, horse, human, pig
응용분야
western blot
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ChIP
ELISA

immunohistochemistry

western blot
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
종별 반응성
dog, human, mouse, pig, rabbit, rat
응용분야
immunohistochemistry

Small Molecule - Blocker

Product Number
설명
Flutamide, ,
mouse, rat, human

Small Molecule - Inhibitor

Product Number
설명
4-(Benzyloxy)phenol, 98%,
rat, human
Galeterone, ≥98% (HPLC),
human
trans-Chalcone, 97%,
rat, human
Spironolactone, 97.0-103.0%,
rat, human
Testosterone propionate, tested according to Ph. Eur.,
human, rat

Small Molecule - Ligand

Product Number
설명
Testosterone, purum, ≥99.0% (HPLC),
human
4-Hydroxyestradiol, ,
rat, human
Tamoxifen, ≥99%,
human, rat
Progesterone, powder, BioReagent, suitable for cell culture,
mouse, human, rat
Progesterone, meets USP testing specifications,
mouse, human, rat

Proteins

Product Number
설명
Androgen receptor (650-920), human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human AR,
human
MISSION® esiRNA, targeting mouse Ar,
mouse