AKT1
v-akt murine thymoma viral oncogene homolog 1
동의어:
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
종:
Human AKT1 (207), Mouse Akt1 (11651), Rat Akt1 (24185), Zebrafish akt1 (101910198), cow AKT1 (280991), domestic cat AKT1 (101087931), dog AKT1 (490878), fruit fly Akt1 (41957), chicken AKT1 (395928), naked mole-rat Akt1 (101700695) ...더
UniProtKB ID:
Clone ID:
- Human(207) Summary: The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
- Mouse(11651) thymoma viral proto-oncogene 1
- Rat(24185) v-akt murine thymoma viral oncogene homolog 1
- Zebrafish(101910198) v-akt murine thymoma viral oncogene homolog 1
- cow(280991) v-akt murine thymoma viral oncogene homolog 1
- domestic cat(101087931) v-akt murine thymoma viral oncogene homolog 1
- dog(490878) v-akt murine thymoma viral oncogene homolog 1
- fruit fly(41957) CG4006 gene product from transcript CG4006-RA
- chicken(395928) v-akt murine thymoma viral oncogene homolog 1
- naked mole-rat(101700695) v-akt murine thymoma viral oncogene homolog 1
- domestic guinea pig(100714724) v-akt murine thymoma viral oncogene homolog 1
- Goat(100860904) v-akt murine thymoma viral oncogene homolog 1
- sheep(100294652) v-akt murine thymoma viral oncogene homolog 1
- sheep(101104184) v-akt murine thymoma viral oncogene homolog 1
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-AKT1 (ab1) antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-phospho-AKT1 (pSer473) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-pan-AKT antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Monoclonal Anti-AKT pS473 antibody produced in mouse, clone 17F6.B11, purified immunoglobulin,
종별 반응성
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Akt (pSer129) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Small Molecule - Inhibitor
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종
Proteins
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설명
종
AKT1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
종
human
Akt1/PKBα Protein, active, 15 µg, Active, recombinant full-length human Akt1, containing N-terminal His6 tag, for use in IP-Kinase Assays & Kinase Assays.,
종
human
SILu™Lite AKT1, RAC-alpha serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
종
human
SILu™Prot AKT1,RAC-alpha serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled,
종
human