ADRA2B
adrenoceptor alpha 2B
동의어:
ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR
종:
Human ADRA2B (151), Mouse Adra2b (11552), Rat Adra2b (24174), Zebrafish adra2b (266751), dog ADRA2B (611658), cow ADRA2B (516422), Horse ADRA2B (100051684), chicken ADRA2B (427631), domestic cat ADRA2B (101090432), sheep ADRA2B (100170318) ...더
UniProtKB ID:
Clone ID:
- Human(151) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. This intronless gene encodes the alpha2B subtype, which was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. [provided by RefSeq, Aug 2011]
- Mouse(11552) adrenergic receptor, alpha 2b
- Rat(24174) adrenoceptor alpha 2B
- Zebrafish(266751) adrenergic, alpha-2B-, receptor
- dog(611658) adrenergic, alpha-2B-, receptor
- cow(516422) adrenergic, alpha-2B-, receptor
- Horse(100051684) adrenoceptor alpha 2B
- chicken(427631) adrenergic, alpha-2B-, receptor
- domestic cat(101090432) adrenoceptor alpha 2B
- sheep(100170318) adrenoceptor alpha 2B
- naked mole-rat(101701692) adrenoceptor alpha 2B
- domestic guinea pig(100135476) adrenergic receptor, alpha 2b
- domestic guinea pig(100727868) adrenoceptor alpha 2B
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Small Molecule - Agonist
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Small Molecule - Antagonist
Antibodies
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종별 반응성
응용분야
Anti-Alpha 2b Adrenergic Receptor, from rabbit, purified by affinity chromatography,
종별 반응성
human
응용분야
immunohistochemistry
western blot
western blot
Anti-ADRA2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-ADRA2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Small Molecule - Blocker
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Small Molecule - Mixed Agonist/Antagonist
esiRNA
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