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Key Documents

A7847

Sigma-Aldrich

Acridine Orange 10-nonyl bromide

Synonym(s):

10-Nonylacridine orange bromide, 3,6-Bis(dimethylamino)-10-nonylacridinium bromide

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About This Item

Empirical Formula (Hill Notation):
C26H38BrN3
CAS Number:
Molecular Weight:
472.50
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Assay

≥90% (HPLC)

Quality Level

form

powder or solid

color

orange to red

mp

≥250 °C (lit.)

solubility

ethanol, DMSO: soluble

ε (extinction coefficient)

76-88 at 491-497 nm in methanol

fluorescence

λex 515-523  nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Br-].CCCCCCCCC[n+]1c2cc(ccc2cc3ccc(cc13)N(C)C)N(C)C

InChI

1S/C26H38N3.BrH/c1-6-7-8-9-10-11-12-17-29-25-19-23(27(2)3)15-13-21(25)18-22-14-16-24(28(4)5)20-26(22)29;/h13-16,18-20H,6-12,17H2,1-5H3;1H/q+1;/p-1

InChI key

DRBHTUDHPPBMCD-UHFFFAOYSA-M

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Application

Metachromatic dye useful as a mitochondrial probe in living cells. This dye has been used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sonia Alcalá et al.
Nature communications, 11(1), 2682-2682 (2020-05-31)
Pancreatic cancer stem cells (PaCSCs) drive pancreatic cancer tumorigenesis, chemoresistance and metastasis. While eliminating this subpopulation of cells would theoretically result in tumor eradication, PaCSCs are extremely plastic and can successfully adapt to targeted therapies. In this study, we demonstrate

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