- Overexpression of the transmembrane protein BST-2 induces Akt and Erk phosphorylation in bladder cancer.
Overexpression of the transmembrane protein BST-2 induces Akt and Erk phosphorylation in bladder cancer.
Oncology letters (2017-07-12)
Yoshinori Shigematsu, Naohide Oue, Yuri Nishioka, Naoya Sakamoto, Kazuhiro Sentani, Yohei Sekino, Shoichiro Mukai, Jun Teishima, Akio Matsubara, Wataru Yasui
PMID28693265
要旨
Bladder cancer, the majority of which is urothelial carcinoma (UC), is a common malignancy worldwide. Genes encoding transmembrane/secretory proteins expressed specifically in certain cancers may be ideal biomarkers for cancer diagnosis and may represent therapeutic targets. In the present study, the expression and function of the bone marrow stromal cell antigen 2