- Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Bioorganic & medicinal chemistry letters (2006-03-28)
Jay P Powers, Shyun Li, Juan C Jaen, Jinqian Liu, Nigel P C Walker, Zhulun Wang, Holger Wesche
PMID16563752
要旨
High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4.