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Merck

[Effects of high-dose cortisone therapy on cognition].

Der Nervenarzt (2005-11-12)
I Uttner, H Tumani
要旨

Treatment with high-dose corticosteroids over 3-5 days reduces the duration and severity of relapses in patients with multiple sclerosis. Since the benefit of this treatment appears to be dose-dependent, application of ultrahigh steroid doses becomes important. On the other hand, data from basic research and clinical studies indicate potential side effects on mnestic functions. Three recently published studies show that treatment with pulsed corticosteroids induces reversible impaired memory. The effects were independent of the dose administered.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
コルチゾン, ≥95%
Supelco
コルチゾン 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®