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  • Preparation and characterization of N-heterocyclic chitosan derivative based gels for biomedical applications.

Preparation and characterization of N-heterocyclic chitosan derivative based gels for biomedical applications.

International journal of biological macromolecules (2009-08-12)
Santosh Kumar, Joydeep Dutta, P K Dutta
要旨

The novel N-heterocyclic chitosan aerogel derivatives were prepared by reacting 79% deacetylated chitosan separately with 4-pyridinecarboxaldehyde and 2,6-pyridinedicarboxaldehyde followed by subsequent solvent exchange into acetone, filteration and lyophilization. The identity of the Schiff bases was confirmed by UV-vis absorption spectroscopy and Fourier transform infrared (FTIR) spectroscopy. The N-heterocyclic chitosan derivatives were evaluated by X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), rheological studies and biological activity. Overall, the N-heterocyclic chitosan derivative based gels open new perspectives in biomedical applications.

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製品内容

Sigma-Aldrich
2,6-ピリジンジカルボキシアルデヒド, 97%