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Merck
  • Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure.

Enantioselective synthesis of furo[2,3-b]furans, a spongiane diterpenoid substructure.

Organic letters (2005-11-18)
Roland Weisser, Weimin Yue, Oliver Reiser
要旨

[structure: see text] A short and enantioselective synthesis of cis-fused 5-oxofuro[2,3-b]furans, being found in many spongiane diterpenoid natural products, is reported starting from inexpensive methyl 2-furoate. Moreover, the acid-catalyzed rearrangement of the furo[2,3-b]furan framework A to B is observed for some derivatives, suggesting a simple connection between natural products differing in the absolute configuration of the 3a,6a ring junction.

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製品番号
ブランド
製品内容

Sigma-Aldrich
2-焦性粘液酸メチル, 98%