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Merck

Phentermine and topiramate extended release (Qsymia™): first global approval.

Drugs (2012-10-09)
Fiona Cameron, Glenn Whiteside, Kate McKeage
要旨

Vivus' proprietary oral capsule containing phentermine and extended-release (ER) topiramate has been approved in the US for the treatment of obesity. Phentermine is an appetite suppressant, while topiramate is an anti-epileptic medication. The once-daily formulation, known as Qsymia™, is designed to produce weight loss by decreasing appetite and increasing satiety. The product is also in clinical development for sleep apnoea syndrome and type 2 diabetes mellitus. This article summarizes the milestones in the development of phentermine/topiramate ER leading to this first approval for obesity.

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製品内容

Supelco
フェンテルミン 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®