- Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA.
Chemical communications (Cambridge, England) (2005-02-23)
Anca Dragulescu-Andrasi, Peng Zhou, Gaofei He, Danith H Ly
PMID15724200
要旨
Guanidine-based peptide nucleic acid (GPNA) with a d-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.
材料