mPredict™ Co-Crystal Prediction Service – Enhancing the Solubility of APIs with AI
When it comes to solid dosage formulations, the most common challenge formulators face is poor solubility. In numbers: 70% of drugs in development are poorly soluble. Co-crystallization is rapidly growing as a technique to address this challenge. This technique combines a promising API with a co-former, resulting in co-crystals with unique properties that improve drug solubility, stability, and bioavailability. But choosing the right co-former can be difficult because the selection is API-specific, depending mainly on purity, structural features, and physical properties. And the only way to find the perfect fit is to test each potential combination by screening different co-formers, via different techniques of co-crystallization, and different solvents, which takes time, uses a lot of chemical materials, is expensive – and often ends without finding a successful formulation.
Offering AI-Powered Solutions for Faster Drug Formulation
With our mPredict™ Co-Crystal Prediction Service – a new AI-based tool that predicts the optimal excipients for your formulation – the struggle to find the right drug and co-former combination ends. Instead, our tool is the key to empowering formulators to develop pharmaceuticals in shorter timeframes while saving resources:
- Accelerates time to clinic: Predicts formulate-ability early in drug development
- Cost effective: Minimizes experimental effort and API screening need
- Innovative: Leverages the power of AI to help you make the right decisions
Based on a broad, high-quality data set, our mPredict™ Co-Crystal Prediction Service covers a large chemical space with potentially many different drug and co-former combinations. It allows us to offer you a service where you submit your chemical compound data, we then run the mPredict™ Co-Crystal Prediction Tool and provide you with a dossier of results and recommendations in just 3-5 days.
Succeeding service packages also provide you an opportunity to request further experiments to reinforce the AI prediction proving that the suggested co-formers actually produce good co-crystals – enabling you to formulate new APIs more efficiently.
Looking to Take Advantage of our New Co-Crystal Prediction Service?
Contact our technical experts and make use of our AI-based tool to find the optimal co-former for your formulation.
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