由来生物
rabbit
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
mouse, human, rat
メーカー／製品名
Upstate®
テクニック
western blot: suitable
アイソタイプ
IgG
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... HDAC5(10014)
特異性
HDAC5
免疫原
KLH-conjugated synthetic peptides corresponding to amino acids 536-545 and 194-206 (C-TKTGELPRQP and C-KSKEPTPGGLNHS) of human HDAC5
アプリケーション
Research Category
エピジェネティクス及び核内機能分子
エピジェネティクス及び核内機能分子
Research Sub Category
ヒストン
ヒストン
Detect HDAC5 also known as histone deacetylase 5 with Anti-HDAC5 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Weaker staining noticed in mouse and rat versus human.
品質
routinely evaluated by immunoblot on HeLa nuclear extract or HeLa whole cell lysate
ターゲットの説明
160 kDa
物理的形状
Protein A chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide.
Format: Purified
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
07-045:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis.
Sian H Leech,Caroline A Evans,Leila Shaw,Chi H Wong,Joanne Connolly,John R Griffiths et al.
Proteomics null
Hongbo Ling et al.
Cell cycle (Georgetown, Tex.), 11(20), 3779-3791 (2012-10-02)
Centrosome duplication is controlled both negatively and positively by a number of proteins. The activities and stabilities of those regulatory proteins are in many cases controlled by posttranslational modifications. Although acetylation and deacetylation are highly common posttranslational modifications, their roles
Lauren E Kernochan et al.
Human molecular genetics, 14(9), 1171-1182 (2005-03-18)
Increasing survival motor neuron 2 (SMN2) gene expression may be an effective strategy for the treatment of spinal muscular atrophy (SMA). Histone deacetylase (HDAC) inhibitors have been shown to increase SMN transcript and protein levels, but the specific role of
Oliver H Krämer et al.
The EMBO journal, 22(13), 3411-3420 (2003-07-04)
Histone-modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. Selective modulators of HDAC isoenzymes could serve as efficient
Syed A H Zaidi et al.
Investigative ophthalmology & visual science, 61(11), 17-17 (2020-09-12)
We determined whether δ-opioid receptor agonist (SNC-121) regulates acetylation homeostasis via controlling histone deacetylases (HDACs) activity and expression in optic nerve head (ONH) astrocytes. ONH astrocytes were treated with SNC-121 (1 µM) for 24 hours. The HDAC activity was measured
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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