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Merck

SART1

squamous cell carcinoma antigen recognized by T cells

別名:
Ara1, HOMS1, SART1259, SNRNP110, Snu66
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9092) Summary: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]
  • Mouse(20227) squamous cell carcinoma antigen recognized by T cells 1
  • Rat(29678) squamous cell carcinoma antigen recognized by T cells
  • naked mole-rat(101706499) squamous cell carcinoma antigen recognized by T cells
  • domestic guinea pig(100725917) squamous cell carcinoma antigen recognized by T cells
  • cow(615704) squamous cell carcinoma antigen recognized by T cells
  • sheep(101103685) squamous cell carcinoma antigen recognized by T cells
  • Zebrafish(436946) squamous cell carcinoma antigen recognised by T cells
  • domestic cat(101080575) squamous cell carcinoma antigen recognized by T cells
  • dog(483721) squamous cell carcinoma antigen recognized by T cells

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-HAF/SART1 Antibody, clone 1-2, clone 1-2, from mouse,
交差性
human
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
抗SART1抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗SART1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗SART1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab3,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗SART1抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SART1,
Species
human
MISSION® esiRNA, targeting mouse Sart1,
Species
mouse