RAB8A
RAB8A, member RAS oncogene family
別名:
MEL, RAB8
Species:
Human RAB8A (4218), Mouse Rab8a (17274), Rat Rab8a (117103), Thale Cress RAB8A (823749), chicken RAB8A (428352), dog RAB8A (403773), domestic cat RAB8A (101092668), Zebrafish rab8a (571897), naked mole-rat Rab8a (101709178), domestic guinea pig Rab8a (100734132) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(4218) Summary: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
- Mouse(17274) RAB8A, member RAS oncogene family
- Rat(117103) RAB8A, member RAS oncogene family
- Thale Cress(823749) small GTP-binding protein ARA3
- chicken(428352) RAB8A, member RAS oncogene family
- dog(403773) RAB8A, member RAS oncogene family
- domestic cat(101092668) RAB8A, member RAS oncogene family
- Zebrafish(571897) RAB8A, member RAS oncogene family
- naked mole-rat(101709178) RAB8A, member RAS oncogene family
- domestic guinea pig(100734132) RAB8A, member RAS oncogene family
- cow(100125881) RAB8A, member RAS oncogene family
- sheep(100302063) RAB8A, member RAS oncogene family
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Antibodies
製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-RAB8A antibody produced in mouse, clone 3G1, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot
Anti-Rab8A Antibody, clone 1N22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, human, monkey, mouse, rat
アプリケーション
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
抗RAB8A抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, canine, human
アプリケーション
ELISA
western blot
western blot
Anti-RAB8A Antibody, from rabbit, purified by affinity chromatography,
交差性
bovine, human, mouse
アプリケーション
western blot
Anti-Rab8 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
western blot