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Merck

PTGIS

prostaglandin I2 (prostacyclin) synthase

別名:
CYP8, CYP8A1, PGIS, PTGI
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(19223) prostaglandin I2 (prostacyclin) synthase
  • Rat(25527) prostaglandin I2 (prostacyclin) synthase
  • cow(282021) prostaglandin I2 (prostacyclin) synthase
  • sheep(101116418) prostaglandin I2 (prostacyclin) synthase
  • Goat(100860894) prostaglandin I2 (prostacyclin) synthase
  • naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
  • domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
  • Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
  • Horse(100071412) prostaglandin I2 (prostacyclin) synthase
  • domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase
  • dog(485919) prostaglandin I2 (prostacyclin) synthase

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗PTGIS抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
抗PTGIS抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, human, mouse, rat
アプリケーション
western blot
Anti-PTGIS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-PTGIS, (C-terminal) antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
抗PTGIS抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Small Molecule - Ligand

製品番号
詳細
Species
フェニルブタゾン, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PTGIS,
Species
human
MISSION® esiRNA, targeting mouse Ptgis,
Species
mouse