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Merck

PIK3R5

phosphoinositide-3-kinase, regulatory subunit 5

別名:
F730038I15Rik, FOAP-2, P101-PI3K, p101
Species:
UniProtKB ID:
遺伝子ID:
  • Human(23533) Summary: Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
  • Mouse(320207) phosphoinositide-3-kinase, regulatory subunit 5, p101
  • Rat(497931) phosphoinositide-3-kinase, regulatory subunit 5
  • cow(614838) phosphoinositide-3-kinase, regulatory subunit 5
  • sheep(101109983) phosphoinositide-3-kinase, regulatory subunit 5
  • naked mole-rat(101721762) phosphoinositide-3-kinase, regulatory subunit 5
  • Domestic Rabbit(100337757) phosphoinositide-3-kinase, regulatory subunit 5
  • domestic guinea pig(100729793) phosphoinositide-3-kinase, regulatory subunit 5
  • Zebrafish(323588) phosphoinositide-3-kinase, regulatory subunit 5
  • chicken(417319) phosphoinositide 3-kinase regulatory subunit 5
  • Horse(100062810) phosphoinositide-3-kinase, regulatory subunit 5
  • domestic cat(101082354) phosphoinositide-3-kinase, regulatory subunit 5
  • dog(612805) phosphoinositide-3-kinase, regulatory subunit 5

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗PIK3R5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗PIK3R5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
Anti-PIK3R5 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
immunohistochemistry
抗PIK3R5抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
proximity ligation assay
western blot
抗PIK3R5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

Small Molecule - Inhibitor

製品番号
詳細
Species
PF-04691502, ≥98% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PIK3R5,
Species
human
MISSION® esiRNA, targeting mouse Pik3r5,
Species
mouse