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Merck

OGG1

8-oxoguanine DNA glycosylase

別名:
HMMH, HOGG1, MUTM, OGH1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4968) Summary: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
  • Mouse(18294) 8-oxoguanine DNA-glycosylase 1
  • Rat(81528) 8-oxoguanine DNA glycosylase
  • fruit fly(31806) CG1795 gene product from transcript CG1795-RA
  • cow(520497) 8-oxoguanine DNA glycosylase
  • domestic cat(101091094) 8-oxoguanine DNA glycosylase
  • dog(484666) 8-oxoguanine DNA glycosylase
  • chicken(771001) 8-oxoguanine DNA glycosylase
  • Thale Cress(838775) 8-oxoguanine-DNA glycosylase 1
  • Zebrafish(791194) 8-oxoguanine DNA glycosylase
  • sheep(101104015) 8-oxoguanine DNA glycosylase
  • naked mole-rat(101697522) 8-oxoguanine DNA glycosylase
  • domestic guinea pig(100731436) 8-oxoguanine DNA glycosylase

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗8-オキソグアニン抗体、クローン483.15, ascites fluid, clone 483.15, Chemicon®,
交差性
human, monkey, mouse, primate, rat
アプリケーション
ChIP
ELISA

immunocytochemistry
Anti-8-Oxoguanine, clone 483.15 Antibody (Ascites Free), clone 483.15, from mouse,
交差性
all, bovine, human, monkey, mouse, rat
アプリケーション
ELISA
immunocytochemistry

immunohistochemistry
抗OGG1抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-OGG1 Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
western blot
Anti-OGG1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human OGG1,
Species
human
MISSION® esiRNA, targeting mouse Ogg1,
Species
mouse