MYLK
myosin light chain kinase
別名:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
Species:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
UniProtKB ID:
遺伝子ID:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- dog(488012) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
- cow(338037) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- sheep(443334) myosin light chain kinase
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Antibodies
Product Number
詳細
交差性
アプリケーション
モノクロナール抗ミオシン軽鎖キナーゼ マウス宿主抗体, clone K36, ascites fluid,
交差性
avian, mammals
アプリケーション
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
western blot
western blot
Small Molecule - Inhibitor
Product Number
詳細
Species
Proteins
Product Number
詳細
Species
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
Species
human
MLCK(1425-1776)、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human