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Merck

MYLK

myosin light chain kinase

別名:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(107589) myosin, light polypeptide kinase
  • Rat(288057) myosin light chain kinase
  • chicken(396445) myosin light chain kinase
  • dog(488012) myosin light chain kinase
  • Horse(100070482) myosin light chain kinase
  • cow(338037) myosin light chain kinase
  • naked mole-rat(101704236) myosin light chain kinase
  • Domestic Rabbit(100009143) myosin light chain kinase
  • domestic guinea pig(100714177) myosin light chain kinase
  • sheep(443334) myosin light chain kinase

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Antibodies

製品番号
詳細
交差性
アプリケーション
モノクロナール抗ミオシン軽鎖キナーゼ マウス宿主抗体, clone K36, ascites fluid,
交差性
avian, mammals
アプリケーション
immunoprecipitation (IP)
microarray

western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
western blot
Anti-MYLK Antibody, clone 1J2U2, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ML-7, powder,
Species
human

Proteins

製品番号
詳細
Species
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
Species
human
MLCK(1425-1776)、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MYLK (2),
Species
human
MISSION® esiRNA, targeting mouse Mylk,
Species
mouse
MISSION® esiRNA, targeting human MYLK (1),
Species
human