コンテンツへスキップ
Merck

MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

別名:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Species:
Human MCL1 (4170), Mouse Mcl1 (17210), Rat Mcl1 (60430), sheep MCL1 (554329), domestic guinea pig Mcl1 (100721658), naked mole-rat Mcl1 (101724340), chicken MCL1 (395674), dog MCL1 (403537), domestic cat MCL1 (493970), cow MCL1 (788087)
UniProtKB ID:
Q07820, B2R6B2, D3DV03, D3DV04, Q9HD91, Q9NRQ3, Q9NRQ4, Q9UHR7
遺伝子ID:
  • Human(4170) Summary: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
  • Mouse(17210) myeloid cell leukemia sequence 1
  • Rat(60430) myeloid cell leukemia sequence 1
  • sheep(554329) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic guinea pig(100721658) myeloid cell leukemia sequence 1 (BCL2-related)
  • naked mole-rat(101724340) myeloid cell leukemia sequence 1 (BCL2-related)
  • chicken(395674) myeloid cell leukemia sequence 1 (BCL2-related)
  • dog(403537) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic cat(493970) myeloid cell leukemia sequence 1 (BCL2-related)
  • cow(788087) myeloid cell leukemia sequence 1 (BCL2-related)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
詳細
Species
G8761
(±)-ゴシポール 綿実由来, ≥95% (HPLC),
Species
human

Antibodies

Product Number
詳細
交差性
アプリケーション
HPA031125
抗MCL1 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
MABC43
Anti-Mcl-1 Antibody, clone RC13, clone RC13, from mouse,
交差性
human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
western blot
AB2910
Anti-Mcl-1 Antibody, serum, Chemicon®,
交差性
human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB4501843
抗MCL1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
western blot
SAB4501844
抗MCL1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot

esiRNA

Product Number
詳細
Species
EHU079921
MISSION® esiRNA, targeting human MCL1,
Species
human
EMU064061
MISSION® esiRNA, targeting mouse Mcl1,
Species
mouse