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Merck

MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

別名:
3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7867) Summary: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
  • Mouse(102626) mitogen-activated protein kinase-activated protein kinase 3
  • Rat(315994) mitogen-activated protein kinase-activated protein kinase 3
  • Zebrafish(790934) mitogen-activated protein kinase-activated protein kinase 3
  • chicken(415917) mitogen-activated protein kinase-activated protein kinase 3
  • dog(484756) mitogen-activated protein kinase-activated protein kinase 3
  • cow(615215) mitogen-activated protein kinase-activated protein kinase 3
  • domestic cat(101096794) mitogen-activated protein kinase-activated protein kinase 3
  • sheep(101118996) mitogen-activated protein kinase-activated protein kinase 3
  • domestic guinea pig(100719631) mitogen-activated protein kinase-activated protein kinase 3
  • Domestic Rabbit(100342292) mitogen-activated protein kinase-activated protein kinase 3
  • naked mole-rat(101717099) mitogen-activated protein kinase-activated protein kinase 3

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MAPKAPK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
Monoclonal Anti-MAPKAPK3 antibody produced in mouse, clone 3F4, purified immunoglobulin, buffered aqueous solution,
交差性
mouse
アプリケーション
ELISA
immunoprecipitation (IP)

western blot
ANTI-MAPKAPK3 antibody produced in mouse, clone 4B11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
ANTI-MAPKAPK3 antibody produced in mouse, clone 1C3, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

Proteins

製品番号
詳細
Species
MAPKAP Kinase 3 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human MAPKAP Kinase 3, amino acids 2-end. Activated using SAPK2a (Catalog #14-587). For use in Kinase Assays.,
Species
human
MAPKAPK3、活性型、GSTタグ付加 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human MAPKAPK3,
Species
human
MISSION® esiRNA, targeting mouse Mapkapk3,
Species
mouse
MISSION® esiRNA, targeting human MAPKAPK3 (2),
Species
human