MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
別名:
FLH21957, HGK, MEKKK4, NIK
Species:
Human MAP4K4 (9448), Mouse Map4k4 (26921), Rat Map4k4 (301363), chicken MAP4K4 (418714), cow MAP4K4 (509109), domestic cat MAP4K4 (101081214), dog MAP4K4 (481331), naked mole-rat Map4k4 (101707800), domestic guinea pig Map4k4 (100723651), sheep MAP4K4 (101109789)
UniProtKB ID:
遺伝子ID:
- Human(9448) Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(26921) mitogen-activated protein kinase kinase kinase kinase 4
- Rat(301363) mitogen-activated protein kinase kinase kinase kinase 4
- chicken(418714) mitogen-activated protein kinase kinase kinase kinase 4
- cow(509109) mitogen-activated protein kinase kinase kinase kinase 4
- domestic cat(101081214) mitogen-activated protein kinase kinase kinase kinase 4
- dog(481331) mitogen-activated protein kinase kinase kinase kinase 4
- naked mole-rat(101707800) mitogen-activated protein kinase kinase kinase kinase 4
- domestic guinea pig(100723651) mitogen-activated protein kinase kinase kinase kinase 4
- sheep(101109789) mitogen-activated protein kinase kinase kinase kinase 4
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗MAP4K4抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Anti-MAP4K4, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot
western blot
Monoclonal Anti-MAP4K4 antibody produced in mouse, clone 2D4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot
ANTI-MAP4K4 antibody produced in mouse, clone 3D9, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot
抗MEKKK 4抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Proteins
製品番号
詳細
Species
HGK (1-328)、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human