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Merck

IL12RB1

interleukin 12 receptor, beta 1

別名:
CD212, IL-12R-BETA1, IL12RB
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3594) Summary: The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(16161) interleukin 12 receptor, beta 1
  • Rat(171333) interleukin 12 receptor, beta 1
  • chicken(101665925) interleukin 12 receptor, beta 1
  • chicken(101749221) interleukin 12 receptor, beta 1
  • cow(524299) interleukin 12 receptor, beta 1
  • domestic cat(101093085) interleukin 12 receptor, beta 1
  • dog(484828) interleukin 12 receptor, beta 1
  • sheep(101110054) interleukin 12 receptor, beta 1
  • domestic guinea pig(100715293) interleukin 12 receptor, beta 1
  • naked mole-rat(101702338) interleukin 12 receptor, beta 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-IL12RB1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-IL12RB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human IL12RB1,
Species
human