コンテンツへスキップ
Merck

GSTM1

glutathione S-transferase mu 1

別名:
GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2944) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14862) glutathione S-transferase, mu 1
  • Rat(24423) glutathione S-transferase mu 1
  • cow(327709) glutathione S-transferase M1
  • cow(783879) glutathione S-transferase mu 1
  • domestic guinea pig(100731426) glutathione S-transferase mu 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

製品番号
詳細
Species
Human GSTM1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
抗GSTM5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-GSTM1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Monoclonal Anti-GSTM1 antibody produced in mouse, clone 3B10, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA

Cell Lines

製品番号
詳細
Species
GST M1-1、ヒト組換え, ,
Species
human

Kits

製品番号
詳細
Species
グルタチオン-S-トランスフェラーゼ (GST) アッセイキット, sufficient for 500 multiwell tests,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GSTM1,
Species
human