GALE
UDP-galactose-4-epimerase
別名:
SDR1E1
Species:
Human GALE (2582), Mouse Gale (74246), Rat Gale (114860), Zebrafish gale (678540), chicken GALE (419686), fruit fly Gale (38076), dog GALE (487373), cow GALE (523154), domestic cat GALE (101099312), domestic guinea pig Gale (100722082) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(2582) Summary: This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Mouse(74246) galactose-4-epimerase, UDP
- Rat(114860) UDP-galactose-4-epimerase
- Zebrafish(678540) UDP-galactose-4-epimerase
- chicken(419686) UDP-galactose-4-epimerase
- fruit fly(38076) UDP-galactose 4'-epimerase
- dog(487373) UDP-galactose-4-epimerase
- cow(523154) UDP-galactose-4-epimerase
- domestic cat(101099312) UDP-galactose-4-epimerase
- domestic guinea pig(100722082) UDP-galactose-4-epimerase
- naked mole-rat(101714632) UDP-galactose-4-epimerase
- sheep(101120144) UDP-galactose-4-epimerase
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗GALE抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
抗GALE抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Gale Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence