F8
coagulation factor VIII, procoagulant component
別名:
AHF, DXS1253E, F8B, F8C, FVIII, HEMA
Species:
Human F8 (2157), Mouse F8 (14069), Rat F8 (302470), Zebrafish f8 (100302404), chicken F8 (422199), cow F8 (100271720), domestic cat F8 (101092751), dog F8 (403875), sheep F8 (100359363), Domestic Rabbit F8 (100303761) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(2157) Summary: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
- Mouse(14069) coagulation factor VIII
- Rat(302470) coagulation factor VIII, procoagulant component
- Zebrafish(100302404) coagulation factor VIII, procoagulant component
- chicken(422199) coagulation factor VIII, procoagulant component
- cow(100271720) coagulation factor VIII, procoagulant component
- domestic cat(101092751) coagulation factor VIII, procoagulant component
- dog(403875) coagulation factor VIII, procoagulant component
- sheep(100359363) coagulation factor VIII, procoagulant component
- Domestic Rabbit(100303761) coagulation factor VIII, procoagulant component
- domestic guinea pig(100720831) coagulation factor VIII, procoagulant component
- naked mole-rat(101725450) coagulation factor VIII, procoagulant component
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Factor VIII antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
western blot
western blot
抗F8抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Monoclonal Anti-F8 antibody produced in mouse, clone 5E9B2, ascites fluid,
交差性
human
アプリケーション
ELISA
western blot
western blot
Anti-Factor VIII Antibody, clone GMA-012, clone GMA-012, Upstate®, from mouse,
交差性
human
アプリケーション
ELISA
western blot
western blot
Anti-vWF (von Willebrand Factor) Antibody, clone GMA-022, clone GMA-022, Upstate®, from mouse,
交差性
human
アプリケーション
western blot
esiRNA
製品番号
詳細
Species