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Merck

DEFA4

defensin, alpha 4, corticostatin

別名:
DEF4, HNP-4, HP-4, HP4
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1669) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Jul 2008]
  • Mouse(13238) defensin, alpha, 4
  • Horse(100307026) defensin, alpha 4, corticostatin

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-DEFA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human DEFA4,
Species
human