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Merck

CLDN18

claudin 18

別名:
SFTA5, SFTPJ
Species:
UniProtKB ID:
遺伝子ID:
  • Human(51208) Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
  • Mouse(56492) claudin 18
  • Rat(315953) claudin 18
  • chicken(429135) claudin 18
  • domestic cat(101093797) claudin 18
  • cow(511460) claudin 18
  • dog(477079) claudin 18
  • sheep(101112106) claudin 18
  • domestic guinea pig(100730947) claudin 18
  • naked mole-rat(101705422) claudin 18

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗CLDN18 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-CLDN18 antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, human, mouse, pig, rabbit, rat
アプリケーション
western blot
Anti-CLDN18, affinity isolated antibody,
交差性
horse, human, mouse, rat
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CLDN18,
Species
human