CFI
complement factor I
別名:
AHUS3, C3BINA, C3b-INA, FI, IF, KAF
Species:
Human CFI (3426), Mouse Cfi (12630), Rat Cfi (79126), sheep CFI (101119307), Domestic Rabbit CFI (100338923), naked mole-rat Cfi (101705881), domestic guinea pig Cfi (100713918), Zebrafish cfi (557557), dog CFI (478515), cow CFI (513197) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(3426) Summary: This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008]
- Mouse(12630) complement component factor i
- Rat(79126) complement factor I
- sheep(101119307) complement factor I
- Domestic Rabbit(100338923) complement factor I
- naked mole-rat(101705881) complement factor I
- domestic guinea pig(100713918) complement factor I
- Zebrafish(557557) complement factor I
- dog(478515) complement factor I
- cow(513197) complement factor I
- Horse(100072852) complement factor I
- domestic cat(101086649) complement factor I
- chicken(428773) complement factor I
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗CFI抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗CFI抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗CFI抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Proteins
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Species
esiRNA
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Species