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Merck

CDKN2C

cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

別名:
INK4C, p18, p18-INK4C
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1031) Summary: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12580) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • Rat(54238) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • Zebrafish(555797) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • cow(505691) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • domestic cat(101086582) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • dog(475359) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • chicken(429104) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • sheep(101109224) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  • domestic guinea pig(100727634) cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Antibody, clone 1Q10Q4, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
immunofluorescence
western blot
Anti-CDKN2C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ロスコビチン, ≥98% (TLC),
Species
human, mouse, rat
オロモウシン, ≥98% (HPLC),
Species
human, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Cdkn2c,
Species
mouse