CASP9
caspase 9, apoptosis-related cysteine peptidase
別名:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Species:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), Zebrafish casp9 (492763), dog CASP9 (487432), Horse CASP9 (100054331), cow CASP9 (100140945), domestic cat CASP9 (768260), chicken CASP9 (426970), domestic guinea pig Casp9 (100714954) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-CASP9 (Cleaved-Asp330), C-Terminal antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 antibody,Mouse monoclonal, clone CAS9, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
microarray
western blot
microarray
western blot
Anti-Caspase 9 antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
製品番号
詳細
Species
Kits
製品番号
詳細
Species
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Species
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Species
human
Proteins
製品番号
詳細
Species
カスパーゼ9 ヒト, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous solution, >2,000 units/mg protein,
Species
human
esiRNA
Small Molecule - Substrate
製品番号
詳細
Species
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Species
mouse, rat, human