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Merck

ALPL

alkaline phosphatase, liver/bone/kidney

別名:
AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
Species:
UniProtKB ID:
遺伝子ID:
  • Human(249) Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
  • Mouse(11647) alkaline phosphatase, liver/bone/kidney
  • Rat(25586) alkaline phosphatase, liver/bone/kidney
  • Zebrafish(393982) alkaline phosphatase, liver/bone/kidney
  • domestic cat(727689) alkaline phosphatase, liver/bone/kidney
  • dog(403548) alkaline phosphatase, liver/bone/kidney
  • chicken(396317) alkaline phosphatase, liver/bone/kidney
  • cow(280994) alkaline phosphatase, liver/bone/kidney
  • naked mole-rat(101725910) alkaline phosphatase, liver/bone/kidney
  • domestic guinea pig(100718683) alkaline phosphatase, liver/bone/kidney
  • sheep(101123195) alkaline phosphatase, liver/bone/kidney

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ELISA

製品番号
詳細
Species
Human ALKP ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
モノクローナル抗FLAG® M2抗体-アルカリフォスファターゼ標識 マウス宿主抗体, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
all
アプリケーション
ELISA
Anti-Alkaline Phosphatase (ALPL) antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗ALPL ウサギ宿主抗体, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
抗ALPL ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-ALPL antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one, 97%,
Species
rat

Kits

製品番号
詳細
Species
アルカリホスファターゼ検出キット, 蛍光, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human ALPL,
Species
human
MISSION® esiRNA, targeting mouse Alpl,
Species
mouse