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Merck

AIRE

autoimmune regulator

別名:
AIRE1, APECED, APS1, APSI, PGA1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
  • Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • Rat(294328) autoimmune regulator
  • Zebrafish(100007662) autoimmune regulator
  • cow(784775) autoimmune regulator
  • domestic cat(101091039) autoimmune regulator
  • dog(487796) autoimmune regulator
  • chicken(429666) autoimmune regulator
  • naked mole-rat(101725873) autoimmune regulator
  • domestic guinea pig(100729880) autoimmune regulator
  • sheep(101102698) autoimmune regulator

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-AIRE Antibody, clone 5H12, clone 5H12, from rat,
交差性
mouse
アプリケーション
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AIRE Antibody, clone Mab155, clone Mab155, 1 mg/mL, from mouse,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry

western blot
抗AIRE抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
western blot
抗AIRE(アイソフォーム1)抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, canine, human, rat
アプリケーション
ELISA
immunohistochemistry

western blot
抗AIRE(アイソフォーム1および2)抗体(AB1) ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ChIP
ELISA

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human AIRE,
Species
human
MISSION® esiRNA, targeting mouse Aire,
Species
mouse