Skip to Content
Merck
All Photos(1)

Key Documents

Safety Information

SRP8046

Sigma-Aldrich

Netrin-1 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

Synonym(s):

ACRP30headless:TNFSF13, NTN1

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in HEK 293 cells

Assay

>95% (SDS-PAGE)

form

lyophilized

mol wt

~90 kDa by SDS-PAGE

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<0.1 EU/μg endotoxin, tested

color

white

UniProt accession no.

O95631

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... NTN1(9423)

General description

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis.

Physical form

Lyophilized from PBS with trehalose and Brij35.

Reconstitution

Reconstitute with 100 μL deionized water.

Other Notes

Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SRP8046-10UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service