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Key Documents

Safety Information

SML3598

Sigma-Aldrich

1PBC

≥98% (HPLC)

Synonym(s):

1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile

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About This Item

Empirical Formula (Hill Notation):
C13H6F3N3O
CAS Number:
Molecular Weight:
277.20
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

-10 to -25°C

SMILES string

OC1=CC(C(F)(F)F)=C(C#N)C2=NC3=CC=CC=C3N21

Biochem/physiol Actions

1PBC is a potent and selective blocker of TMEM16A calcium-activated chloride channel that interacts with the anion pore. Also, 1PBC is a potent inhibitor of TMEM16F channel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

SML3598-10MG:
SML3598-50MG:
SML3598-VAR:
SML3598-BULK:


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