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Safety Information

S2192

Sigma-Aldrich

S9 from Liver, Pooled

from mouse(CD-1), male, 20 mg/mL protein basis, vial of 1.0 mL

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About This Item

UNSPSC Code:
12161501
NACRES:
NA.47

biological source

mouse (CD-1)

Quality Level

packaging

vial of 1.0 mL

concentration

20 mg/mL protein

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

mouse ... Rps9(76846)

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Biochem/physiol Actions

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

Physical form

Supplied as a solution in 150 mM KCl, 50 mM Tris buffer, pH 7.2 and 2 mM EDTA.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S2192-BULK:
S2192-1VL-PW:
S2192-VAR:
S2192-1VL:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)

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