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Safety Information

M9191

Sigma-Aldrich

Microsomes from Liver, Pooled

from rat(Sprague-Dawley), female

Synonym(s):

lab equipment accessory

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About This Item

UNSPSC Code:
12161501
NACRES:
NA.47

biological source

rat (Sprague-Dawley)

Quality Level

200

form

liquid

specific activity

≥20 units/mg protein, pH 7.4, 37 °C

packaging

vial of ~10 mg

shipped in

dry ice

storage temp.

−70°C

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Biochem/physiol Actions

Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.

Unit Definition

One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M9191-1VL-PW:
M9191-BULK:
M9191-VAR:
M9191-1VL:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL5361
SLCL3368
SLCC3970
SLCC1342
SLCC1028

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