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O5636

Sigma-Aldrich

9,12-Octadecadiynoic acid

≥98%

Synonym(s):

ODYA, Ro 3-1314

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About This Item

Empirical Formula (Hill Notation):
C18H28O2
CAS Number:
2012-14-8
Molecular Weight:
276.41
MDL number:
MFCD00797685
UNSPSC Code:
12352106
PubChem Substance ID:
329818915
NACRES:
NA.77

Quality Level

200

Assay

≥98%

form

crystalline

mp

45-46 °C

solubility

water: slightly soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCCCC#CCC#CCCCCCCCC(O)=O

InChI

1S/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-5,8,11-17H2,1H3,(H,19,20)

InChI key

KDYILQLPKVZDGB-UHFFFAOYSA-N

Biochem/physiol Actions

Potent cyclooxygenase and lipoxygenase inhibitor.

Caution

Oxygen and light sensitive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

O5636-1MG-LBL:
O5636-1MG:
O5636-VAR:
O5636-BULK:
O5636-1MG-PW:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Hitchcock et al.
British journal of pharmacology, 72(4), 689-695 (1981-04-01)
1. 5,8,11,14-Eicosatetraynoic acid (ETYA) inhibited the antigen-induced contractions of tracheal spirals obtained from actively sensitized guinea-pigs. Consistent data were obtained only when the spirals were treated with indomethacin. 2. ETYA did not affect histamine-induced contractions of indomethacin-treated tracheal spirals. 3.
Ning Wang et al.
Frontiers in physiology, 9, 583-583 (2018-06-08)
Background: Perivascular adipose tissue (PVAT) exerts anti-contractile effects on visceral arteries by release of various perivascular relaxing factors (PVRFs) and opening voltage-gated K+ (Kv) channels in vascular smooth muscle cells (VSMCs). Palmitic acid methyl ester (PAME) has been proposed as
David R Colquhoun et al.
Proteomics, 15(12), 2066-2077 (2015-04-29)
Protein acylation plays a critical role in protein localization and function. Acylation is essential for human immunodeficiency virus 1 (HIV-1) assembly and budding of HIV-1 from the plasma membrane in lipid raft microdomains and is mediated by myristoylation of the

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