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Safety Information

N8000

Sigma-Aldrich

1-Naphthyl butyrate

esterase substrate, ≥99% (GC), liquid

Synonym(s):

Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester

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About This Item

Linear Formula:
CH3CH2CH2CO2C10H7
CAS Number:
Molecular Weight:
214.26
Beilstein:
2558646
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

1-Naphthyl butyrate, esterase substrate

description

esterase substrate

Quality Level

Assay

≥99% (GC)

form

liquid

refractive index

n20/D 1.571 (lit.)

bp

125-130 °C/1 mmHg (lit.)

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

density

1.091 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CCCC(=O)Oc1cccc2ccccc12

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

InChI key

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

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Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Biochem/physiol Actions

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Substrates

Esterase substrate.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

143.6 °F - closed cup

Flash Point(C)

62 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 4: Flammable liquids
Type 2 petroleums
Hazardous rank III
Water insoluble liquid

JAN Code

N8000-10G:
N8000-250MG:
N8000-5G:
N8000-1G:
N8000-H:
N8000-BULK:
N8000-VAR:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Juan C Sanchez-Hernandez
Journal of hazardous materials, 350, 136-143 (2018-02-23)
The activation of biochar (carbonaceous material generated by pyrolysis of biomass) with extracellular enzymes generated from soil biological processes was studied via a 2-month microcosm using earthworms. The isolation of biochar particles (post-incubated biochar) from earthworm-treated soils allowed to confirm
L Zhang et al.
Microbiology (Reading, England), 144 ( Pt 2), 555-559 (1998-03-11)
Albicidins are a family of phytotoxins and antibiotics which play an important role in the pathogenesis of sugarcane leaf scald disease. The albA gene from Klebsiella oxytoca encodes a protein which inactivates albicidin by heat-reversible binding. Albicidin ligand binding to
Esterases of the flounder (Platichthys flesus, Pleuronectidae, Teleostei): development of an identification protocol using starch gel electrophoresis and characterization of loci
Berrebi P, et al.
Experientia, 46(8), 863-867 (1990)
R B Miller et al.
Journal of biochemical and biophysical methods, 3(6), 345-354 (1980-12-01)
We have developed a spectrophotometric assay method which continuously records esterase activity at 510 nm by monitoring absorbance changes due to the formation of a diazo dye complex. In our method, alpha-naphthyl ester substrates are hydrolyzed by enzymatic action to
Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes.
Bozdech MJ and Bainton DF
The Journal of Experimental Medicine, 153(1), 182-195 (1981)

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