ML0014

Alanine Metabolite Library

• UNSPSC Code: 41116107
• NACRES: NA.28

Properties

• storage temp.: −20°C
• Quality Level: 200

Description

General description

Alanine metabolism known also as Glucose-Alanine cycle or Cahill cycle is the process in which muscles utilize amino acids for their energetic needs.

• Glutamate and Pyruvate are transformed into Alanine and α-ketoglutarate in the muscle, through the actions of Alanine aminotransferase (AST) and Pyridoxal Phosphate.
• The α-ketoglutarate transforms to Glutamate through the actions of glutamate dehydrogenase with an addition of ammonia. But, in this pathway, the ammonia is excluded from the muscles.
• The Alanine passes through the blood stream and into the liver. In the liver, the Alanine and a-ketoglutarate transform to Pyruvate and Glutamate by the actions of Alanine aminotransferase (AST).
• The Pyruvate transforms to glucose by the Cori cycle (Gluconeogenesis) and returns to the muscle from the blood stream.

Packaging

Components:

Each vial is packaged individually and contains 10 mg of the Alanine pathway metabolite standards.

Kit Components Also Available Separately

• A2754 Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC) 10 mg
• A2252 Adenosine 5′-monophosphate monohydrate, from yeast, ≥97% 10 mg
• A2383 Adenosine 5′-triphosphate disodium salt hydrate, Grade I, ≥99%, from microbial 10 mg
• B4501 Biotin, ≥99% (HPLC), lyophilized powder 10 mg
• G7126 Glycine, ReagentPlus^®, ≥99% (HPLC) 10 mg
• G10601 Glyoxylic acid monohydrate, 98% 10 mg
• A7627 L-Alanine, ≥98% (TLC) 10 mg
L-Glutamic acid 10 mg
O4126 Oxaloacetic acid, ≥97% (HPLC) 10 mg
K1750 α-Ketoglutaric acid, ≥98.5% (NaOH, titration) 10 mg
P9255 Pyridoxal 5′-phosphate hydrate, ≥98% 10 mg
P8010 Sodium pyrophosphate tetrabasic, ≥95% 10 mg
Sodium pyruvate 10 mg

See All (13)

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H290,H302,H315,H317,H318
• Precautionary Statements: P234 - P261 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials