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G5011

Sigma-Aldrich

Glucan from baker′s yeast (S. cerevisiae)

≥98.00%

Synonym(s):

Glucosan

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About This Item

CAS Number:
9012-72-0
EC Number:
232-739-1
MDL number:
MFCD00466924
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

bakers yeast (S. cerevisiae)

Quality Level

200

Assay

≥98.00%

form

powder

color

white to faint yellow

solubility

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

storage temp.

2-8°C

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General description

Glucan is a natural polysaccharide. They are carbohydrates forming structural components, which is found in the cell walls of yeast, fungi, seaweed and cereals.

Application

Glucan from baker′s yeast (S. cerevisiae) has been used:
  • for immune stimulation
  • to stimulate mRNA expression of a sigma class glutathione S-transferase (GST) in hemocytes
  • to study its effects in rainbow trout intestinal epithelial cell line (RTgutGC)

Biochem/physiol Actions

Glucan enhances anti-infectious immunity, prevents cancer growth, lowers stress and reduces cholesterol level. It has immunostimulatory property. It maintains blood sugar level and rejuvenates skin.

Preparation Note

Prepared by the method of Bacon, et al.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G5011-25MG-PW:
G5011-10MG:
G5011-100MG-PW:
G5011-VAR:
G5011-BULK:
G5011-5MG:
G5011-100MG:
G5011-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A novel LRR and Ig domain-containing protein could function as an immune effector in Crassostrea gigas
Wang X, et al.
Fish & Shellfish Immunology (2019)
Cheng Man Lun et al.
Immunobiology, 221(8), 889-903 (2016-03-30)
The purple sea urchin, Strongylocentrotus purpuratus, possesses a sophisticated innate immune system that responds to microbes effectively by swift expression of the highly diverse Sp185/333 gene family. The Sp185/333 proteins are predicted to have anti-pathogen functions based on inducible gene
Effects of beta-glucans on the immune system
Akramiene D, et a l.
Medicina, 43(8), 597-597 (2007)
Rainbow Trout (Oncorhynchus Mykiss) Intestinal Epithelial Cells as a Model for Studying Gut Immune Function and Effects of Functional Feed Ingredients
Wang J, et al.
Frontiers in immunology, 10 (2019)
Antonella Torosantucci et al.
The Journal of experimental medicine, 202(5), 597-606 (2005-09-09)
To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic beta-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in
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