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Key Documents

Safety Information

G2388

Sigma-Aldrich

Globulins Cohn fraction II, III human

lyophilized powder

Synonym(s):

Human globulins, Powder globulins

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About This Item

CAS Number:
68476-36-8
EC Number:
270-678-2
MDL number:
MFCD01114254
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human

Quality Level

300

form

lyophilized powder

composition

Protein, 60-85% TCA-Biuret

concentration

60-85% (biuret)

impurities

HIV 1 and 2, HBsAg and HCV, source material tested negative

storage temp.

2-8°C

Application

Globulins Cohn fraction II, III human has been used to replace α and β subunits to determine the role of α and β subunits of phosphorylase kinase.

Other Notes

Primarily γ- and β-globulins

Physical form

Contains NaCl

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G2388-VAR:
G2388-BULK:
G2388-CP:
G2388-10G:
G2388PROC:
G2388-5G:
G2388-1G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inhibition of the catalytic subunit of phosphorylase kinase by its alpha/beta subunits.
Paudel HK and Carlson GM
The Journal of biological chemistry, 262(25), 11912-11915 (1987)
N E Riera et al.
International journal of laboratory hematology, 32(1 Pt 1), e96-105 (2009-07-15)
Immune humoral neutropenia (Np) could be the consequence of anti-polymorphonuclear neutrophil (PMN) antibodies, circulating immune complexes (CIC) and/or antibodies against myeloid precursors. Granulocyte immunofluorescence test (GIFT) and a leukoagglutination technique (LAGT) assays are recommended for its diagnosis. Fifty adult patients
P Muret et al.
Skin pharmacology : the official journal of the Skin Pharmacology Society, 6(1), 45-51 (1993-01-01)
The binding of 5-methoxypsoralen (5-MOP) to human serum and blood fractions was studied by equilibrium dialysis associated to high-performance liquid chromatography. 5-MOP serum binding was 95% and kept constant in the range of therapeutic concentrations. Albumin was the main binding
Fenxia Hou et al.
ALTEX, 37(3), 451-468 (2020-04-24)
There are currently no skin sensitization assays based on T cell activation. We built a novel in vitro model to assess T cell activation and test its performance to discriminate skin sensitizers from non-sensitizers using 52 reference chemicals. Jurkat Clone

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