Key Documents
Safety Information
108315
TRIS hydrochloride
EMPROVE® EVOLVE
Pharma Manufacturing
Synonym(s):
Trizma® hydrochloride, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride
About This Item
Recommended Products
biological source
synthetic
Quality Level
description
Manufactured under appropriate controls for use as a raw material in BioProcessing
product line
EMPROVE® EVOLVE
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, tested
Microbial, tested
Trace Metals, tested
useful pH range
7.0-9.0
pKa (25 °C)
8.1
suitability
suitable for (Suitable for use as a raw material in bioprocessing)
suitable for manufacturing use
foreign activity
Cytotoxicity, contains (tested)
DNase, contains (tested)
NICKase, contains (tested)
Protease, contains (tested)
RNase, contains (tested)
SMILES string
Cl.NC(CO)(CO)CO
InChI
1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
InChI key
QKNYBSVHEMOAJP-UHFFFAOYSA-N
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General description
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Application
Tris HCl is used as the conjugate buffer component with Tris/Tromethamine/Trizma in biopharmaceutical buffer formulations (both upstream and downstream applications), electrophoresis separations and diagnostic reagent formulations.
Other Notes
Legal Information
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
JAN Code
1083150100:
1083155000:
1083150000:
1083150003:
1083159999:
1083159050:
1083150100-KC:
1083159025:
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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