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Safety Information

T0781

Supelco

3,5,5,-Trimethyloxazolidine-2,4-dione

analytical standard

Synonym(s):

Trimethadione

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About This Item

Empirical Formula (Hill Notation):
C6H9NO3
CAS Number:
127-48-0
Molecular Weight:
143.14
EC Number:
204-845-8
MDL number:
MFCD00047084
UNSPSC Code:
41116107
PubChem Substance ID:
329826621
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN1C(=O)OC(C)(C)C1=O

InChI

1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3

InChI key

IRYJRGCIQBGHIV-UHFFFAOYSA-N

Gene Information

human ... CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H312 + H332,H360

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T0781-1G:
T0781-10G:
T0781-50G:
T0781-BULK:
T0781-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number

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Tammye L Fleeman et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 71(3), 185-190 (2004-07-30)
Congenital membranous ventricular septal defects (VSD) have been shown to close during postnatal development in rats [Solomon et al., Teratology 55:185-194, 1997]. Although they may differ in size, spontaneous and treatment-related VSD are histologically similar; however, the postnatal fate of
Education and imaging. Hepatobiliary and pancreatic: oral therapy for pancreatic duct stones.
A Hashimoto et al.
Journal of gastroenterology and hepatology, 21(9), 1496-1496 (2006-08-17)
H Nakamura et al.
Journal of clinical pharmacy and therapeutics, 26(6), 417-424 (2001-11-28)
The trimethadione (TMO) tolerance test was performed to evaluate its usefulness in the assessment of hepatic functional reserve in patients with biliary atresia. Nineteen patients with biliary atresia after hepatic portoenterostomy (age range: 2 months to 25 years; sex: 6
Haiyan Shen et al.
Hearing research, 226(1-2), 52-60 (2007-02-13)
Cochlear noise injury is the second most frequent cause of sensorineural hearing loss, after aging. Because calcium dysregulation is a widely recognized contributor to noise injury, we examined the potential of calcium channel blockers to reduce noise-induced hearing loss (NIHL)
N Kurata et al.
Xenobiotica; the fate of foreign compounds in biological systems, 28(11), 1041-1047 (1999-01-08)
1. Caucasian liver samples were used in this study. N-demethylation of trimethadione (TMO) to dimethadione (DMO) was monitored in the presence of chemical inhibitors of CYPs, such as fluconazole, quinidine, dimethyl-nitrosamine, acetaminophen, phenacetin, chlorzoxazone and mephenytoin. Trimethadione N-demethylation was selectively
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