PHR1790

Eicosapentaenoic Acid Ethyl Ester

Pharmaceutical Secondary Standard: Certified Reference Material

• Synonym(s): cis-5,8,11,14,17-Eicosapentaenoic acid ethyl ester
• Empirical Formula (Hill Notation): C₂₂H₃₄O₂
• CAS Number: 86227-47-6
• Molecular Weight: 330.50
• UNSPSC Code: 12352211
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to Ph. Eur. E0085000; traceable to USP 1234307
• API family: eicosapentaenoic acid
• form: liquid
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• application(s): pharmaceutical
• storage temp.: -10 to -25°C
• InChI: 1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5+,9-8+,12-11+,15-14+,18-17+
• InChI key: SSQPWTVBQMWLSZ-LRKAYDMASA-N

Description

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Docosahexaenoic Acid Ethyl Ester is the ethyl ester of docosahexaenoic acid, an essential omega-3 fatty acid.

Application

This pharmaceutical secondary standard can also be used as follows:

• Development and validation of a reverse phase high-performance liquid chromatography-tandem mass spectrometry (RP-HPLC-MS/MS) method to determine eicosapentaenoic acid and docosahexaenoic acid in their ethyl ester forms
• Simulated moving bed (SMB) chromatographic separation of ethyl esters of eicosapentaenoic acid and docosahexaenoic acids

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2773 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): >320.0 °F
• Flash Point(C): > 160 °C