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Key Documents

Safety Information

N2515

Supelco

D-Norpropoxyphene maleate salt

analytical standard

Synonym(s):

1,2-Diphenyl-3-methyl-4-(methylamino)-2-butyl propionate

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About This Item

Empirical Formula (Hill Notation):
C21H27NO2 · C4H4O4
CAS Number:
Molecular Weight:
441.52
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OC(=O)\C=C/C(O)=O.CCC(=O)OC(Cc1ccccc1)(C(C)CNC)c2ccccc2

InChI

1S/C21H27NO2.C4H4O4/c1-4-20(23)24-21(17(2)16-22-3,19-13-9-6-10-14-19)15-18-11-7-5-8-12-18;5-3(6)1-2-4(7)8/h5-14,17,22H,4,15-16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HCQPFYNZJNOOKN-BTJKTKAUSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

N2515-50MG-PW:
N2515-10MG:
N2515-VAR:
N2515-50MG:
N2515-BULK:


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J W King et al.
Journal of analytical toxicology, 18(4), 217-219 (1994-07-01)
We have found that in using the Toxi-Lab Spec VC MP3 column we were able to easily identify and quantitate both propoxyphene and the major metabolite, norpropoxyphene, in a single extraction using urine as a matrix. Samples were screened using
F T Horrigan et al.
The Journal of general physiology, 107(2), 243-260 (1996-02-01)
Voltage-dependent ionic currents were recorded from squid giant fiber lobe neurons using the whole-cell patch-clamp technique. When applied to the bathing solution, methadone was found to block IK, I Na and I Ca. Both I Na and I Ca were
R J Flanagan et al.
British journal of clinical pharmacology, 28(4), 463-469 (1989-10-01)
1. The pharmacokinetics of dextropropoxyphene (D) and nordextropropoxyphene (ND) have been studied in 12 healthy young (21-28 years) and 12 healthy elderly (70-79 years) male and female subjects. Each received 65 mg D and plasma D and ND concentrations were
Y Horsmans et al.
Journal of hepatology, 21(3), 283-291 (1994-09-01)
In an attempt to design a liver function test which takes into account both portal-systemic shunting and hepatocellular dysfunction, we investigated a group of patients with cirrhosis with or without surgical porta-caval shunt for d-propoxyphene and its major metabolite, norpropoxyphene
P P Rop et al.
Journal of chromatography, 615(2), 357-364 (1993-06-02)
Dextromoramide, propoxyphene and its main metabolite, norpropoxyphene, were determined in blood after solid-liquid extraction by means of an HPLC method using photodiode-array detection. Two cases of fatal overdose resulting from abuse of the two drugs are presented. In case 1

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