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34213

Supelco

Pazufloxacin

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H15FN2O4
CAS Number:
127045-41-4
Molecular Weight:
318.30
MDL number:
MFCD00865012
UNSPSC Code:
41116107
PubChem Substance ID:
329754899
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

C[C@H]1COc2c3N1C=C(C(O)=O)C(=O)c3cc(F)c2C4(N)CC4

InChI

1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1

InChI key

XAGMUUZPGZWTRP-ZETCQYMHSA-N

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General description

Chemical structure: quinolone
Pazufloxacin is a fluoroquinolone antibiotic, which shows broad spectrum activity in anti-infective chemotherapy.

Application

Pazufloxacin may be used as a reference standard in the determination of pazufloxacin in serum and plasma samples using high performance liquid chromatography coupled with fluorescence detector (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

34213-BULK:
34213-VAR:
34213-25MG:

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ5177
SZBF005XV
SZBC079XV
SZBA221XV
SZBA221X

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Shinzaburo Minami et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 122(2), 161-178 (2003-08-02)
Pazufloxacin mesilate (PZFX: Pasil INJECTION, Pazucross INJECTION) is a novel injectable quinolone antibiotic that was discovered by Toyama Chemical Co., Ltd. and codeveloped by Toyama Chemical Co. Ltd. and Mitsubishi Pharma Corporation. Laboratory studies indicated that PZFX reached high plasma
First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma.
Sousa J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 930, 104-111 (2013)
A P Johnson
Current opinion in investigational drugs (London, England : 2000), 1(1), 52-57 (2001-03-16)
Toyama Chemical Co Ltd is developing pazufloxacin (T-3761), an orally active synthetic quinolone antibiotic, which is awaiting registration following successful clinical trials that demonstrated its pharmacological similarities to tosufloxacin (Toyama Chemical Co) with respect to clinical efficacy, adverse effects and
Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
Watabe S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 878(19), 1555-1561 (2010)
Zhoumin Li et al.
Biosensors & bioelectronics, 87, 874-880 (2016-09-24)
In this paper, we report a sensitive, simple and inexpensive analytical method for the immunoassay microarray based on a smartphone in which various harmful substances in milk could be assayed. Tetracyclines (TCs) and Quinolones (QNs) were selected as the model
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