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34130

Supelco

Fusarenon X solution

100 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one, FusX

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About This Item

Empirical Formula (Hill Notation):
C17H22O8
CAS Number:
23255-69-8
Molecular Weight:
354.35
EC Number:
200-835-2
MDL number:
MFCD00078778
UNSPSC Code:
41116107
PubChem Substance ID:
329754836
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@]24CO4

InChI

1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9-,11-,12-,13-,14-,15-,16-,17+/m1/s1

InChI key

XGCUCFKWVIWWNW-CAYGJDLQSA-N

General description

Certan Vial
Fusarenon X, is a trichothecene mycotoxin, which is produced by Fusarium nivale fungi, naturally occurring in crops such as wheat and barley.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Group 4: Flammable liquids
Type 1 petroleums
Hazardous rank II
Water insoluble liquid

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

34130-2ML-BULK:
34130-2ML:4548173258560

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3026
BCCG5947
BCCF6544
BCCC8509
BCCB3655

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Low tumor incidence in rats with long-term feeding of fusarenon-X, a cytotoxic trichothecene produced by Fusarium nivale
Saito M, et al.
The Japanese Journal of Experimental Medicine, 50, 293-302 (1980)
Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release
Miura K, et al.
Toxicology, 172, 103-112 (2002)
The fates of trichothecene mycotoxins, nivalenol and fusarenon-X, in mice
Poapolathep A, et al.
Toxicon, 41, 1047-1054 (2003)
J Li et al.
The Journal of veterinary medical science, 59(3), 191-199 (1997-03-01)
Male 5-week-old Wistar rats orally (po) administered with fusarenon-X (FX) 1.5 mg/kg and control rats po-treated with distilled water were sacrificed at 0-48 hr after gavage. FX-administered rats showed significant dilatation of the stomach with increased fluid contents at 1-24
S Bony et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(3), 457-465 (2006-12-13)
This study aims to assess the genotoxic potential of nivalenol (NIV) and fusarenon X (FusX), produced by various Fusarium on cereals. Toxins were applied in time and dose-dependent experiments to the human enterocyte-like Caco-2 cell-line, both in dividing (undifferentiated) and
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