Skip to Content
Merck
All Photos(1)

Documents

Safety Information

33656

Supelco

Semicarbazide hydrochloride

VETRANAL®, analytical standard

Synonym(s):

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
NH2CONHNH2 · HCl
CAS Number:
563-41-7
Molecular Weight:
111.53
Beilstein:
3593642
EC Number:
209-247-0
MDL number:
MFCD00013009
UNSPSC Code:
41116107
PubChem Substance ID:
329754605
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

175-177 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl.NNC(N)=O

InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Semicarbazide hydrochloride may be used as a stabilizing agent for the determination of norepinephrine in plasma samples using stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Semicarbazide hydrochloride may be used in the synthesis of 4-nitrobenzaldehyde semicarbazone via reaction with 4-nitrobenzaldehyde.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H301,H314,H361fd,H373

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

Target Organs

Bone

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Group 5: Self-reactive substances
Hydrazine derivates
Hazardous rank II
2nd self-reactive materials

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

33656-100MG-R:
33656-VAR-R:
33656-BULK-R:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCG5696
BCCG5699
BCBV0190
BCBV0139
SZBD324XV

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography?tandem mass spectrometry
Leitner A, et al.
Journal of Chromatography A, 939, 49-58 (2001)
Determination of norepinephrine in small volume plasma samples by stable-isotope dilution gas chromatography-tandem mass spectrometry with negative ion chemical ionization.
Kuhlenbeck LD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 738(2), 319-330 (2000)
Robert McCracken et al.
Food chemistry, 136(3-4), 1562-1567 (2012-12-01)
There is evidence that semicarbazide (SEM), a marker for the banned nitrofuran nitrofurazone, can arise from other, unrelated sources. Recently, Belgium rejected 54 consignments of Bangladeshi freshwater shrimp (Macrobrachium rosenbergii), following a laboratory decision to test meat and exoskeleton combined.
Miwa Takahashi et al.
Toxicologic pathology, 38(4), 598-605 (2010-05-08)
To compare the susceptibility to toxicity of semicarbazide hydrochloride (SEM-HCl) between young and adult rats, 3- and 20-week-old female SD rats were given a diet containing SEM-HCl at 0, 500, or 1,000 ppm and 0 or 1,000 ppm, respectively, for
Kazimiera Cwiek-Ludwicka
Roczniki Panstwowego Zakladu Higieny, 61(4), 341-347 (2010-01-01)
The release of the substances from food packaging into food triggers the problem for food safety and is the matter of particular interest in the European Commission (EC) and Member States. The problems concerning the presence of these substances in
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service