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33347

Supelco

AOZ

VETRANAL®, analytical standard

Synonym(s):

3-Amino-2-oxazolidinone, NSC 111187, NSC 196570, NSC 38250

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About This Item

Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
80-65-9
Molecular Weight:
102.09
Beilstein:
109430
EC Number:
201-299-2
MDL number:
MFCD00020871
UNSPSC Code:
41116107
PubChem Substance ID:
329754490
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

63-69 °C

suitability

passes test for identity

application(s)

clinical testing

format

neat

SMILES string

NN1CCOC1=O

InChI

1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2

InChI key

KYCJNIUHWNJNCT-UHFFFAOYSA-N

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General description

AOZ, also known as 3-amino-2-oxazolidinone, is a metabolite of the synthetic nitrofuran veterinary antibiotic ― furazolidone.

Application

The analytical standard can be used as follows:
  • Development of an electrochemical impedimetric immunosensor based on immobilization of a monoclonal antibody on a gold electrode, to determine AOZ in six food samples
  • Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry
  • Detection and measurement of AOZ in tissue samples obtained from four animals by immunochromatography test stripes based on colloidal gold-monoclonal antibody
  • LC-MS/MS analysis of nitrofuran and nitroimidazole metabolite residues in honey samples after their extraction by a modified QuEChERS-based method
  • Screening of nitrofuran metabolite residues from shrimp muscle samples by an HPLC method combined with diode array detection

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

33347-BULK-R:
33347-VAR-R:
33347-50MG-R:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC3222
BCCD9383
BCCC4145
BCBZ9884
BCBX1759

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Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
Diblikova I, et al.
Analytica Chimica Acta, 540, 285-292 (2005)
Quan Wang et al.
Analytical and bioanalytical chemistry, 410(1), 223-233 (2017-11-01)
There is an urgent need for the rapid and simultaneous detection of multiple analytes present in a sample matrix. Here, a multiplex immunochromatographic test (multi-ICT) was developed that successfully allowed for the rapid and simultaneous detection of four major nitrofuran
Jinyan Gong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1146, 122018-122018 (2020-04-26)
This study established a validated analytical method for the first time on the determination of nitrofuran metabolites, including semicarbazide (SEM), 1-aminohydantoin (AHD), 3-amino-2-oxazolidinone (AOZ) and 3-amino-5-morpholinomethyl-2-oxazolinone (AMOZ) in gelatin Chinese medicine. A C18 column with the mobile phase consisting of
Pierre Guichard et al.
Food chemistry, 342, 128389-128389 (2020-12-04)
LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. The nitrofuran metabolites investigated were as follows: 3-amino-2-oxazolidinone (AOZ), 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 1-aminohydantoine (AHD), semicarbazide (SEM) and 3,5-dinitrosalicylic acid hydrazide (DNSH). The
A rapid derivatization method for analyzing nitrofuran metabolites in fish using ultra-performance liquid chromatography-tandem mass spectrometry.
Siyang Wu et al.
Food chemistry, 310, 125814-125814 (2019-11-23)

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